An experiment was conducted in farmers’ field during wet seasons of 2003 and 2004 to study the effect of nutrient management in potato through vermicompost and urea each with sole and in different proportions on growth, productivity, nutrient uptake, economics and soil fertility of succeeding wet season rice in potatosesame-rice cropping system. Integrated use of plant nutrients in potato through vermicompost and urea had significant influence on growth, productivity, nutrient uptake, economics and soil nutrient reserve after rice as evidenced from pooled data. Supplementation of 40-60 % recommended dose (RD) of nitrogen from vermicompost and rest from chemical fertilizers in potato exhibited the highest growth, yield attributes and yield, net return, return per rupee investment and nutrient uptake in rice. These treatments also left higher residual available nitrogen, phosphorus and potassium after rice harvest. Use of 100 % RD of N entirely from chemical fertilizers or farmers’ practice in potato had lesser residual effect on succeeding wet season rice compared with integrated use of organic (vermicompost) and chemical sources.