A field experiment was conducted at Mohanpur, West Bengal to study the integrated nutrient management on productivity, quality improvement of crops and fertility build up of soil under rice-onion-cowpea cropping sequence. Application of 75% recommended dose (RD) of N, P and K along with 25% RD of N through Neematex (neem seed powder + oilcake) produced highest yield of different crops. The highest benefit: cost ratio was recorded with 75% RD of N, P and K + 25% RD of N through FYM. Application of 25% RD of N through organic sources viz. FYM or Neematex or Biomax or in-situ green manuring with Sesbania to rice in conjunction, with 75% RD of N, P and K to all the crops in sequence improved the system productivity, production efficiency, quality of crops, nutrient up take and nutrient status of soil in rice-onion-cowpea cropping sequence.