Field experiment was conducted at Chiplima, Sambalpur, Odisha during wet and dry seasons of 2011-2013 to assess the effect of nitrogen application, fungicidal sprays and varietal resistance on leaf blast disease severity and yield of rice. There was a progressive increase of leaf blast severity with full doses of nitrogen as compared to the application of two-third of the recommended dose in the susceptible variety Swarna. During wet season, the best treatment observed was Swarna with 2-3 sprays of Tricyclazole 75 WP @0.6 g l^-1 and 2/3rd nitrogen level showing 89.65% disease control, whereas during dry season, treatment having the resistant variety Pratikshya with 100% N was the best giving 96.92% disease control over check and was significantly superior to other treatments. The resistant variety with 100% N showed constantly low disease severity throughout the experiment in both the seasons. Two to three applications of Tricyclazole 75 WP @0.6 g l^-1 along with two third recommended dose of N showed maximum increase in yield (43.74% in dry season and 59.96% in wet season) in the susceptible variety.